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Ligand · 294

294 · N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide

294, N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide (C19 H18 F3 N O6 S, 445.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
294
Formula
C19 H18 F3 N O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

294 in 2 structures; the first of them:

  • 3B8Z · High Resolution Crystal Structure of the Catalytic Domain of ADAMTS-5 (Aggrecanase-2) · 294 A801 · binds HIS373, ASP377, THR378, LEU379, GLY380, HIS403, PHE406, THR407 and 12 more
  • 3B8Z · High resolution crystal structure of the catalytic domain of adamts-5 (aggrecanase-2) · 294 A801 · binds HIS373, ASP377, THR378, LEU379, GLY380, HIS403, PHE406, THR407 and 12 more

Residues it binds most

HIS 4, LEU 4, SER 4, THR 4, ILE 4, ASP 4, GLU 4, GLY 4, PHE 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion

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