GL1X · GenesisL1 explorer

Ligand · 1T0

1T0 · 4-[(3R)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide

1T0, 4-[(3R)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide (C27 H27 F N6 O2, 486.6 g/mol), in the MolNFT structures on GenesisL1…

Component
1T0
Formula
C27 H27 F N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

1T0 in 2 structures; the first of them:

  • 7FAL · Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with… · 1T0 A901 · binds ARG470, GLU472, LYS474, GLN475, PRO476, PHE479, LEU480, ARG481 and 12 more
  • 7FAL · Co-crystal structure of toxoplasma gondii prolyl tRNA synthetase (tgprs) in complex with… · 1T0 A901 · binds ARG470, GLU472, LYS474, GLN475, PRO476, PHE479, LEU480, ARG481 and 12 more

Residues it binds most

ARG 4, THR 4, ALA 4, GLN 4, PHE 4, GLY 4, CYS 4, GLU 4, LEU 4, LYS 4 (residue and the binding sites it lines).

Found with

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