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Ligand · 1RP

1RP · 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide

1RP, 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide (C10 H13 F N3 O9 P, 369.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues…

Component
1RP
Formula
C10 H13 F N3 O9 P
Class
ligand
Structures
4
PDB entries
2

Binding sites

1RP in 4 structures; the first of them:

  • 4KN6 · Crystal structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with… · 1RP A301 · binds LYS68, GLU133, ASP134, ILE135, ILE136, ASP137, THR138, GLY139 and 8 more
  • 7DFG · Structure of COVID-19 RNA-dependent RNA polymerase bound to favipiravir · 1RP P1201 · binds U20, U10, A11, LYS545, VAL557, ASP623, THR680, SER682 and 3 more
  • 4KN6 · Crystal structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with… · 1RP A301 · binds LYS68, GLU133, ASP134, ILE135, ILE136, ASP137, THR138, GLY139 and 8 more
  • 7DFG · Structure of COVID-19 RNA-dependent RNA polymerase bound to favipiravir · 1RP P1201 · binds U20, U10, A11, LYS545, VAL557, ASP623, THR680, SER682 and 3 more

Residues it binds most

ASP 4, LYS 4, THR 4, ILE 2, U 2, VAL 4, A 2, ASN 2, GLU 2, GLY 2 (residue and the binding sites it lines).

Found with

  • POP · Pyrophosphate 2-
  • MG · Magnesium ion
  • ZN · Zinc ion

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