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Ligand · 1M4

1M4 · (4R)-2'-amino-6-bromo-1',2,2-trimethyl-2,3-dihydrospiro[chromene-4,4'-imidazol]-5'(1'H)-one

1M4, (4R)-2'-amino-6-bromo-1',2,2-trimethyl-2,3-dihydrospiro[chromene-4,4'-imidazol]-5'(1'H)-one (C14 H16 Br N3 O2, 338.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
1M4
Formula
C14 H16 Br N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

1M4 in 2 structures; the first of them:

  • 4JOO · Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors · 1M4 A503 · binds LEU78, ASP80, GLY82, SER83, VAL117, TYR119, TRP124, PHE156 and 6 more
  • 4JOO · Spirocyclic beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors · 1M4 A503 · binds LEU78, ASP80, GLY82, SER83, VAL117, TYR119, TRP124, PHE156 and 6 more

Residues it binds most

ASP 2, GLY 2, ILE 2, TRP 2, LEU 2, PHE 2, SER 2, THR 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • NI · Nickel (II) ion

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