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Ligand · 1EA

1EA · 6-fluoro-2-[2-methyl-4-phenoxy-5-(propan-2-yl)phenyl]quinoline-4-carboxylic acid

1EA, 6-fluoro-2-[2-methyl-4-phenoxy-5-(propan-2-yl)phenyl]quinoline-4-carboxylic acid (C26 H22 F N O3, 415.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
1EA
Formula
C26 H22 F N O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

1EA in 2 structures; the first of them:

  • 4IGH · High resolution crystal structure of human dihydroorotate dehydrogenase bound with… · 1EA A503 · binds TYR38, MET43, LEU46, GLN47, PRO52, ALA55, HIS56, LEU58 and 14 more
  • 4IGH · High resolution crystal structure of human dihydroorotate dehydrogenase bound with… · 1EA A503 · binds TYR38, MET43, LEU46, GLN47, PRO52, ALA55, HIS56, LEU58 and 14 more

Residues it binds most

LEU 2, ALA 2, MET 2, PHE 2, PRO 2, THR 2, TYR 2, VAL 2, ARG 2, GLN 2 (residue and the binding sites it lines).

Found with

  • FMN · Flavin mononucleotide
  • ORO · Orotic acid
  • ZWI · 3-[decyl(dimethyl)ammonio]propane-1-sulfonate
  • GOL · Glycerol

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