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Ligand · 19K

19K · N~4~-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N~1~,N~1~-dimethyl-2-nitrobenzene-1,4-diamine

19K, N~4~-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N~1~,N~1~-dimethyl-2-nitrobenzene-1,4-diamine (C17 H18 N6 O2 S, 370.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
19K
Formula
C17 H18 N6 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

19K in 2 structures; the first of them:

  • 3SW7 · Crystal Structure of the CDK2 in complex with thiazolylpyrimidine inhibitor · 19K A299 · binds ILE10, VAL18, ALA31, VAL64, PHE80, GLU81, PHE82, LEU83 and 8 more
  • 3SW7 · Crystal structure of the CDK2 in complex with thiazolylpyrimidine inhibitor · 19K A299 · binds ILE10, VAL18, ALA31, VAL64, PHE80, GLU81, PHE82, LEU83 and 8 more

Residues it binds most

ALA 2, ASP 2, GLN 2, LEU 2, PHE 2, VAL 2, GLU 2, HIS 2, ILE 2, LYS 2 (residue and the binding sites it lines).

Found with

  • ACE · Acetyl group

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