Ligand · 130
130 · 2-(2-hydroxy-biphenyl)-1H-benzoimidazole-5-carboxamidine
130, 2-(2-hydroxy-biphenyl)-1H-benzoimidazole-5-carboxamidine (C20 H16 N4 O, 328.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…
- Component
- 130
- Formula
- C20 H16 N4 O
- Class
- ligand
- Structures
- 6
- PDB entries
- 3
Binding sites
130 in 6 structures; the first of them:
- 1GJ5 · Selectivity at S1, H2O displacement, upa, tpa, SER190/ALA190 protease, structure-based… · 130 H410 · binds LEU41, CYS42, HIS57, CYS58, TYR60A, TRP60D, LYS60F, ASP189 and 11 more
- 1GJB · Engineering inhibitors highly selective for the S1 sites of SER190 trypsin-like serine… · 130 B251 · binds VAL41, CYS42, HIS57, CYS58, ASP60A, ASP189, SER190, CYS191 and 10 more
- 1GJC · Engineering inhibitors highly selective for the S1 sites of SER190 trypsin-like serine… · 130 B251 · binds VAL41, CYS42, HIS57, CYS58, ASP189, SER190, CYS191, GLN192 and 9 more
- 1GJ5 · Selectivity at S1, H2O displacement, upa, tpa, SER190/ALA190 protease, structure-based… · 130 H410 · binds LEU41, CYS42, HIS57, CYS58, TYR60A, TRP60D, LYS60F, ASP189 and 11 more
- 1GJB · Engineering inhibitors highly selective for the S1 sites of SER190 trypsin-like serine… · 130 B251 · binds VAL41, CYS42, HIS57, CYS58, ASP60A, ASP189, SER190, CYS191 and 10 more
- 1GJC · Engineering inhibitors highly selective for the S1 sites of SER190 trypsin-like serine… · 130 B251 · binds VAL41, CYS42, HIS57, CYS58, ASP189, SER190, CYS191, GLN192 and 9 more
Residues it binds most
CYS 6, GLY 6, SER 6, VAL 6, ASP 6, TRP 6, HIS 6, GLN 4, ALA 2, GLU 2 (residue and the binding sites it lines).
Found with
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