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Ligand · 10F

10F · N-({4-[{[(2R,4S,4aR,6S,8aS)-2-amino-4-hydroxydecahydropteridin-6-yl]methyl}(formyl)amino]phenyl}carbonyl)-D-glutamic acid

10F, N-({4-[{[(2R,4S,4aR,6S,8aS)-2-amino-4-hydroxydecahydropteridin-6-yl]methyl}(formyl)amino]phenyl}carbonyl)-D-glutamic acid (C20 H29 N7 O7, 479.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
10F
Formula
C20 H29 N7 O7
Class
ligand
Structures
2
PDB entries
1

Binding sites

10F in 2 structures; the first of them:

  • 3HY3 · Structure of human MTHFS with 10-formyltetrahydrofolate · 10F A501 · binds LYS18, PHE55, LEU56, SER57, MET58, GLU61, PRO81, TYR83 and 9 more
  • 3HY3 · Structure of human mthfs with 10-formyltetrahydrofolate · 10F A501 · binds LYS18, PHE55, LEU56, SER57, MET58, GLU61, PRO81, TYR83 and 9 more

Residues it binds most

LYS 2, MET 2, PHE 2, PRO 2, TYR 2, ARG 2, GLU 2, GLY 2, ILE 2, LEU 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • NI · Nickel (II) ion

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