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Ligand · 0VF

0VF · 4-{[(3S)-1-{7-[(3,4-dimethoxyphenyl)amino][1,3]thiazolo[5,4-d]pyrimidin-5-yl}pyrrolidin-3-yl]carbamoyl}benzoic acid

0VF, 4-{[(3S)-1-{7-[(3,4-dimethoxyphenyl)amino][1,3]thiazolo[5,4-d]pyrimidin-5-yl}pyrrolidin-3-yl]carbamoyl}benzoic acid (C25 H24 N6 O5 S, 520.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
0VF
Formula
C25 H24 N6 O5 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

0VF in 2 structures; the first of them:

  • 4FYO · Crystal structure of spleen tyrosine kinase complexed with… · 0VF A701 · binds LEU377, GLY378, SER379, GLY380, VAL385, ALA400, VAL433, MET448 and 12 more
  • 4FYO · Crystal structure of spleen tyrosine kinase complexed with N-{(S)-1… · 0VF A701 · binds LEU377, GLY378, SER379, GLY380, VAL385, ALA400, VAL433, MET448 and 12 more

Residues it binds most

GLY 2, LEU 2, ALA 2, GLU 2, MET 2, VAL 2, ARG 2, ASN 2, ASP 2, LYS 2 (residue and the binding sites it lines).

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