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Ligand · 0TT

0TT · 1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-[[(5R)-1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-methyl-2,4-bis(oxidanylidene)-1,3-diazinan-5-yl]methyl]pyrimidine-2,4-dione

0TT, 1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-[[(5R)-1-[(2R,4S,5R)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-methyl-2,4-bis(oxidanylidene)-1,3-diazinan-5-yl]methyl]pyrimidine-2,4-dione (C20 H28 N4 O10, 484.5 g/mol), in…

Component
0TT
Formula
C20 H28 N4 O10
Class
ligand
Structures
6
PDB entries
3

Binding sites

0TT in 6 structures; the first of them:

  • 4FHD · Spore photoproduct lyase complexed with dinucleoside spore photoproduct · 0TT A408 · binds SER76, LYS77, PRO78, SER79, TYR98, THR102, GLU137, ALA139 and 9 more
  • 4FHF · Spore photoproduct lyase C140A mutant with dinucleoside spore photoproduct · 0TT A409 · binds SER76, LYS77, PRO78, SER79, TYR98, THR102, GLU137, ALA139 and 10 more
  • 4RH1 · Spore photoproduct lyase C140A/S76C mutant with bound AdoMet and dinucleoside spore… · 0TT A409 · binds CYS76, LYS77, PRO78, SER79, TYR98, THR102, GLU137, ALA139 and 10 more
  • 4FHD · Spore photoproduct lyase complexed with dinucleoside spore photoproduct · 0TT A408 · binds SER76, LYS77, PRO78, SER79, TYR98, THR102, GLU137, ALA139 and 9 more
  • 4FHF · Spore photoproduct lyase C140A mutant with dinucleoside spore photoproduct · 0TT A409 · binds SER76, LYS77, PRO78, SER79, TYR98, THR102, GLU137, ALA139 and 10 more
  • 4RH1 · Spore photoproduct lyase C140A/S76C mutant with bound adomet and dinucleoside spore… · 0TT A409 · binds CYS76, LYS77, PRO78, SER79, TYR98, THR102, GLU137, ALA139 and 10 more

Residues it binds most

THR 6, ARG 6, GLU 6, TYR 6, ALA 6, SER 6, ILE 6, LYS 6, PRO 6, VAL 6 (residue and the binding sites it lines).

Found with

  • EEM · [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium
  • SF4 · Iron/sulfur cluster
  • SO4 · Sulfate ion
  • POP · Pyrophosphate 2-

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