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Ligand · 0QR

0QR · N-(6-aminopyridin-2-yl)-4-fluorobenzenesulfonamide

0QR, N-(6-aminopyridin-2-yl)-4-fluorobenzenesulfonamide (C11 H10 F N3 O2 S, 267.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
0QR
Formula
C11 H10 F N3 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

0QR in 2 structures; the first of them:

  • 4EPX · Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation · 0QR A203 · binds LYS5, LEU6, VAL7, GLU37, ASP54, ILE55, LEU56, GLU62 and 5 more
  • 4EPX · Discovery of small molecules that bind to K-RAS and inhibit sos- mediated activation · 0QR A203 · binds LYS5, LEU6, VAL7, GLU37, ASP54, ILE55, LEU56, GLU62 and 5 more

Residues it binds most

GLU 2, LEU 2, ASP 2, GLN 2, GLY 2, ILE 2, LYS 2, MET 2, THR 2, TYR 2 (residue and the binding sites it lines).

Found with

  • GDP · Guanosine-5'-diphosphate
  • MG · Magnesium ion

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