071 · 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

Binding sites

071 in 2 structures; the first of them:

• 3KB7 · Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor · 071 A1 · binds LEU59, GLY60, CYS67, ALA80, LYS82, VAL114, LEU130, GLU131 and 11 more
• 3KB7 · Crystal structure of polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor · 071 A1 · binds LEU59, GLY60, CYS67, ALA80, LYS82, VAL114, LEU130, GLU131 and 11 more

Residues it binds most

LEU 2, ARG 2, CYS 2, GLU 2, GLY 2, ALA 2, ASN 2, ASP 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

• ZN · Zinc ion
• TLA · L(+)-tartaric acid