MolNFT v2 · #88317 · protein
B-Raf Kinase V600E mutant in complex with a diarylthiazole B-Raf Inhibitor
4CQE: “B-Raf Kinase V600E mutant in complex with a diarylthiazole B-Raf Inhibitor”. X-ray diffraction at 2.3. MolNFT v2 #88317 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4CQE
- Type
- protein
- Length
- 498 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.3
- Source
- HOMO SAPIENS
- UniProt
- D7PBN4
Structure
x-ray diffraction · resolution 2.3 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 250 | — | D7PBN4 |
| B | — | protein | 248 | — | D7PBN4 |
Compared structures
- 4CQE · B-RAF kinase V600E mutant in complex with a diarylthiazole B-RAF inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D7PBN4
- Elsewhere: RCSB PDB 4CQE · PDBe 4CQE · UniProt D7PBN4
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