MolNFT v2 · #63919 · RNA
Crystal structure of guanine riboswitch bound to 6-O-methylguanine
3FO6: “Crystal structure of guanine riboswitch bound to 6-O-methylguanine”. X-ray diffraction at 1.9, 2 ligands (NCO, 6GO), 2 pockets (best druggability 0.72). MolNFT v2 #63919 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3FO6
- Type
- RNA
- Length
- 67 nucleotides
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.9
- Molecule
- Guanine riboswitch
- Ligands
- NCO, 6GO
- Pockets
- 2 · best druggability 0.72
Structure
x-ray diffraction · resolution 1.9 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanine riboswitch | rna | 67 | — | — |
Ligands and binding sites
- NCO · Cobalt hexammine(iii) · ligand · 9 copies · chains A
- 6GO · 6-O-methylguanine · ligand · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 914 | 0.72 | 0.77 | 41 | ACT, NCO |
| 2 | 218 | 0.47 | 0.75 | 21 | 6GO |
Compared structures
- 3FO6 · Crystal structure of guanine riboswitch bound to 6-O- methylguanine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3FO6 · PDBe 3FO6
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