MolNFT v2 · #51057 · protein
Ivy Desaturase Structure
2UW1 · Plastid DELTA4 multifunctional acyl-acyl carrier protein…: “Ivy Desaturase Structure”. X-ray diffraction at 1.95, 3 ligands (GVM, FE, NA), 6 pockets (best druggability 0.78). MolNFT v2 #51057 on GenesisL1: 3D structure, binding…
- PDB
- 2UW1
- Type
- protein
- Length
- 665 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.95
- Source
- HEDERA HELIX
- Molecule
- Plastid DELTA4 multifunctional acyl-acyl carrier protein desaturase
- EC
- 1.14.99.6
- Ligands
- GVM, FE, NA
- Pockets
- 6 · best druggability 0.78
Structure
x-ray diffraction · resolution 1.95 · 2 distinct chains · 68% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Plastid DELTA4 multifunctional acyl-acyl carrier protein desaturase (EC 1.14.99.6) | protein | 327 | 70% helix, 2% strand | — |
| B | Plastid DELTA4 multifunctional acyl-acyl carrier protein desaturase (EC 1.14.99.6) | protein | 338 | 66% helix, 2% strand | — |
Ligands and binding sites
- GVM · (3R)-3-hydroxy-5,5-dimethylhexanoic acid · ligand · 2 copies · chains A, B
- FE · Fe (III) ion · metal · 4 copies · chains A, B
- NA · Sodium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 430 | 0.78 | 0.86 | 48 | GVM |
| 2 | 346 | 0.74 | 0.85 | 45 | GVM |
| 3 | 50 | 0.36 | 0.80 | 16 | empty |
| 4 | 85 | 0.34 | 0.74 | 15 | empty |
| 5 | 55 | 0.32 | 0.76 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 2843 Ų buried · 46 hydrogen bonds · protein-protein
Compared structures
- 2UW1 · Ivy desaturase structure · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2UW1 · PDBe 2UW1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.