MolNFT v2 · #228465 · protein
CryoEM structure of the fragment-4 (4074-4421) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1
9FLX · The grappling hook protein A in the bacterium Aureispira…: “CryoEM structure of the fragment-4 (4074-4421) in the grappling hook protein A (GhpA) in the bacterium…”. Electron microscopy at 3.6, 20 pockets (best druggability 0.44).…
- PDB
- 9FLX
- Type
- protein
- Length
- 2,436 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.6
- Source
- Aureispira sp. CCB-QB1
- Molecule
- The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1
- Pockets
- 20 · best druggability 0.44
Structure
electron microscopy · resolution 3.6 · 1 distinct chain · 3% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A, C, D, E, F, G | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | protein | 348 | 3% helix, 40% strand | — |
Pockets
20 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 141 | 0.44 | 0.76 | 20 | empty |
| 2 | 137 | 0.44 | 0.76 | 19 | empty |
| 3 | 133 | 0.43 | 0.76 | 21 | empty |
| 4 | 122 | 0.43 | 0.76 | 18 | empty |
| 5 | 125 | 0.42 | 0.76 | 20 | empty |
Interfaces
7 interfaces between chains.
- F–G · 822 Ų buried · 6 hydrogen bonds · protein-protein
- E–F · 822 Ų buried · 6 hydrogen bonds · protein-protein
- B–A · 821 Ų buried · 6 hydrogen bonds · protein-protein
- D–E · 815 Ų buried · 5 hydrogen bonds · protein-protein
- B–G · 815 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 28 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 9FLX · PDBe 9FLX
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