MolNFT v2 · #220932 · protein
Apo structure of protein crystal of Tri17
8TF7 · AMP-binding protein: “Apo structure of protein crystal of Tri17”. X-ray diffraction at 2.45, 8 pockets (best druggability 0.73). MolNFT v2 #220932 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8TF7
- Type
- protein
- Length
- 1,033 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.45
- Source
- Streptomyces tsukubensis
- Molecule
- AMP-binding protein
- UniProt
- A0A5H2UY12
- Pockets
- 8 · best druggability 0.73
Structure
x-ray diffraction · resolution 2.45 · 2 distinct chains · 29% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | AMP-binding protein | protein | 516 | 29% helix, 27% strand | A0A5H2UY12 |
| B | AMP-binding protein | protein | 517 | 30% helix, 26% strand | A0A5H2UY12 |
Pockets
8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 953 | 0.73 | 0.76 | 110 | empty |
| 2 | 1042 | 0.72 | 0.76 | 116 | empty |
| 3 | 712 | 0.71 | 0.78 | 48 | empty |
| 4 | 211 | 0.65 | 0.84 | 41 | empty |
| 5 | 203 | 0.62 | 0.82 | 36 | empty |
Interfaces
1 interface between chains.
- A–B · 911 Ų buried · 14 hydrogen bonds · protein-protein
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A5H2UY12
- Elsewhere: RCSB PDB 8TF7 · PDBe 8TF7 · UniProt A0A5H2UY12
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