MolNFT v2 · #219494 · protein
Structure of SemD in complex
8S5T · Effector SemD: “Structure of SemD in complex”. X-ray diffraction at 3.3, 3 pockets (best druggability 0.73). MolNFT v2 #219494 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8S5T
- Type
- protein
- Length
- 336 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.3
- Source
- Chlamydia; Rattus norvegicus
- Molecule
- Effector SemD; Neural Wiskott-Aldrich syndrome protein
- UniProt
- Q9Z7M7, A0A6P6IA87
- Pockets
- 3 · best druggability 0.73
Structure
x-ray diffraction · resolution 3.3 · 2 distinct chains · 71% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D | Effector SemD | protein | 243 | 77% helix, 0% strand | Q9Z7M7 |
| A | Neural Wiskott-Aldrich syndrome protein | protein | 93 | 55% helix, 5% strand | A0A6P6IA87 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 454 | 0.73 | 0.82 | 42 | empty |
| 2 | 142 | 0.43 | 0.76 | 28 | empty |
| 3 | 61 | 0.28 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- D–A · 1669 Ų buried · 24 hydrogen bonds · protein-protein
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Z7M7
- Every structure of UniProt A0A6P6IA87
- Elsewhere: RCSB PDB 8S5T · PDBe 8S5T · UniProt Q9Z7M7 · UniProt A0A6P6IA87
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.