MolNFT v2 · #219205 · protein
In meso structure of apolipoprotein N-acyltransferase, Lnt, from Escherichia coli in 7.10 monoacylglycerol
8RQR: “In meso structure of apolipoprotein N-acyltransferase, Lnt, from Escherichia coli in 7.10 monoacylglycerol”. X-ray diffraction at 2.19, 1 ligand (A1H2K), 3 pockets (best druggability 0.76). MolNFT v2 #219205 on GenesisL1: 3D…
- PDB
- 8RQR
- Type
- protein
- Length
- 511 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.19
- Source
- Escherichia coli
- Molecule
- Apolipoprotein N-acyltransferase
- EC
- 2.3.1.269
- UniProt
- P23930
- Ligands
- A1H2K
- Pockets
- 3 · best druggability 0.76
Structure
x-ray diffraction · resolution 2.19 · 1 distinct chain · 53% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Apolipoprotein N-acyltransferase (EC 2.3.1.269) | protein | 511 | 53% helix, 16% strand | P23930 |
Ligands and binding sites
- A1H2K · 7.10 monoacylglycerol (S-form) · ligand · 8 copies · chains A
- GOL · Glycerol · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 850 | 0.76 | 0.79 | 68 | A1H2K |
| 2 | 196 | 0.62 | 0.83 | 29 | empty |
| 3 | 65 | 0.33 | 0.75 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23930
- Elsewhere: RCSB PDB 8RQR · PDBe 8RQR · UniProt P23930
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.