MolNFT v2 · #218998 · protein

S103A mutant of the BTB domain of ZBTB8A from Xenopus laevis

8RIR · Zinc finger and BTB domain-containing protein 8A.1-A: “S103A mutant of the BTB domain of ZBTB8A from Xenopus laevis”. X-ray diffraction at 3.72, 1 pocket (best druggability 0.69). MolNFT v2 #218998 on GenesisL1: 3D structure…

PDB: 8RIR
Type: protein
Length: 245 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.72
Source: Xenopus laevis
Molecule: Zinc finger and BTB domain-containing protein 8A.1-A
UniProt: Q0IH98
Pockets: 1 · best druggability 0.69

Structure

x-ray diffraction · resolution 3.72 · 2 distinct chains · 51% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zinc finger and BTB domain-containing protein 8A.1-A	protein	123	51% helix, 12% strand	Q0IH98
B	Zinc finger and BTB domain-containing protein 8A.1-A	protein	122	51% helix, 12% strand	Q0IH98

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.69	0.96	23	empty

Interfaces

1 interface between chains.

A–B · 1387 Å² buried · 16 hydrogen bonds · protein-protein

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q0IH98
Elsewhere: RCSB PDB 8RIR · PDBe 8RIR · UniProt Q0IH98

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