MolNFT v2 · #216267 · protein
Alpha-1-antitrypsin - Sydney variant (G192C)
8P4J: “Alpha-1-antitrypsin - Sydney variant (G192C)”. X-ray diffraction at 1.91, 1 pocket (best druggability 0.58). MolNFT v2 #216267 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8P4J
- Type
- protein
- Length
- 356 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.91
- Source
- Homo sapiens
- Molecule
- Alpha-1-antitrypsin
- UniProt
- P01009
- Pockets
- 1 · best druggability 0.58
Structure
x-ray diffraction · resolution 1.91 · 1 distinct chain · 30% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-1-antitrypsin | protein | 356 | 30% helix, 33% strand | P01009 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 105 | 0.58 | 0.85 | 21 | empty |
Compared structures
- P01009 · AlphaFold monomer V2.0 prediction for alpha-1-antitrypsin (P01009) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01009
- Elsewhere: RCSB PDB 8P4J · PDBe 8P4J · UniProt P01009
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