MolNFT v2 · #214625 · protein

Crystal structure of Adenosine triphosphate phosphoribosyltransferase from Acinetobacter baumannii at 2.18 A resolution

8JUK · ATP phosphoribosyltransferase: “Crystal structure of Adenosine triphosphate phosphoribosyltransferase from Acinetobacter baumannii at 2.18 A…”. X-ray diffraction at 2.181, 8 pockets (best druggability 0.65). MolNFT v2 #214625 on…

PDB: 8JUK
Type: protein
Length: 454 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.181
Source: Acinetobacter baumannii
Molecule: ATP phosphoribosyltransferase
EC: 2.4.2.17
UniProt: V5VGC6
Pockets: 8 · best druggability 0.65

Structure

x-ray diffraction · resolution 2.181 · 1 distinct chain · 31% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	ATP phosphoribosyltransferase (EC 2.4.2.17)	protein	227	31% helix, 30% strand	V5VGC6

Ligands and binding sites

ACT · Acetate ion · additive · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	499	0.65	0.77	52	ACT
2	321	0.59	0.77	32	empty
3	136	0.46	0.77	19	empty
4	122	0.44	0.77	20	empty
5	97	0.40	0.76	17	empty

Interfaces

1 interface between chains.

A–B · 1333 Å² buried · 8 hydrogen bonds · protein-protein

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt V5VGC6
Elsewhere: RCSB PDB 8JUK · PDBe 8JUK · UniProt V5VGC6

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