MolNFT v2 · #211448 · DNA

Crystal structure of Cd2+-bound DNA aptamer T22C mutant

8GZM · 25-mer DNA: “Crystal structure of Cd2+-bound DNA aptamer T22C mutant”. X-ray diffraction at 2.55, 2 ligands (BA, CD), 1 pocket (best druggability 0.24). MolNFT v2 #211448 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 8GZM
Type: DNA
Length: 25 nucleotides
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.55
Molecule: 25-mer DNA
Ligands: BA, CD
Pockets: 1 · best druggability 0.24

Structure

x-ray diffraction · resolution 2.55 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	25-mer DNA	dna	25	—	—

Ligands and binding sites

BA · Barium ion · metal · 3 copies · chains A
CD · Cadmium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.24	0.72	13	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 8GZM · PDBe 8GZM

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