MolNFT v2 · #211299 · protein

Chitin-active AA10 LPMO (GbpA) from Vibrio campbellii

8GUM · GlcNAc-binding protein A: “Chitin-active AA10 LPMO (GbpA) from Vibrio campbellii”. X-ray diffraction at 2.35, 7 pockets (best druggability 0.81). MolNFT v2 #211299 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 8GUM
Type: protein
Length: 824 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.35
Source: Vibrio campbellii ATCC BAA-1116
Molecule: GlcNAc-binding protein A
UniProt: A7N3J0
Pockets: 7 · best druggability 0.81

Structure

x-ray diffraction · resolution 2.35 · 2 distinct chains · 11% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GlcNAc-binding protein A	protein	464	11% helix, 39% strand	A7N3J0
B	GlcNAc-binding protein A	protein	360	11% helix, 36% strand	A7N3J0

Pockets

7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	989	0.81	0.82	124	empty
2	528	0.67	0.78	71	empty
3	365	0.65	0.79	41	empty
4	371	0.64	0.79	49	empty
5	159	0.51	0.79	25	empty

Interfaces

1 interface between chains.

A–B · 3523 Å² buried · 52 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

A7N3J0 · AlphaFold monomer V2.0 prediction for glcnac-binding protein a (A7N3J0) · a predicted model of the same protein · chain B against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A7N3J0
Elsewhere: RCSB PDB 8GUM · PDBe 8GUM · UniProt A7N3J0

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