MolNFT v2 · #203621 · protein
Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide and non-acceptor peptide bound
8AGC: “Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide and non-acceptor…”. Electron microscopy at 3.1, 10 ligands (CPL, PTY, ELU). MolNFT v2 #203621 on GenesisL1: 3D structure, binding sites and…
- PDB
- 8AGC
- Type
- protein
- Length
- 2,151 residues
- Chains
- 9
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.1
- Source
- Saccharomyces cerevisiae; SYNTHETIC CONSTRUCT
- UniProt
- A0A6A5Q0M3, A0A8H8UM72, Q92316, A0A8H4BUV6, A0A6A5PXA1, A0A6V8S2Y6, A0A8H8ULL1, A0A6A5Q3S9
- Ligands
- CPL, PTY, ELU, 323, NAG, MAN, GLC, BMA, NDG, MN
Structure
electron microscopy · resolution 3.1 · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 697 | — | A0A6A5Q0M3 |
| B | — | protein | 33 | — | A0A8H8UM72 |
| C | — | protein | 85 | — | Q92316 |
| D | — | protein | 109 | — | A0A8H4BUV6 |
| E | — | protein | 438 | — | A0A6A5PXA1 |
| F | — | protein | 258 | — | A0A6V8S2Y6 |
| G | — | protein | 394 | — | A0A8H8ULL1 |
| H | — | protein | 131 | — | A0A6A5Q3S9 |
| P | — | protein | 6 | — | — |
Ligands and binding sites
- CPL · 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine · ligand · 4 copies · chains A, B, E, C, D, F, G
- PTY · Phosphatidylethanolamine · ligand · 2 copies · chains A, F, H
- ELU · phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate · ligand · chains A
- 323 · 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate · ligand · chains A, H, P
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains A, G, E
- MAN · alpha-D-mannopyranose · sugar · 9 copies · chains F, G, A
- GLC · alpha-D-glucopyranose · sugar · 3 copies · chains D, G
- BMA · beta-D-mannopyranose · sugar · 2 copies · chains G, A
- NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · sugar · chains A, P
- MN · Manganese (II) ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- Q92316 · AlphaFold monomer V2.0 prediction for dolichyl- diphosphooligosaccharide--protein… · a predicted model of the same protein · chain C against A, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A6A5Q0M3
- Every structure of UniProt A0A8H8UM72
- Every structure of UniProt Q92316
- Every structure of UniProt A0A8H4BUV6
- Every structure of UniProt A0A6A5PXA1
- Every structure of UniProt A0A6V8S2Y6
- Every structure of UniProt A0A8H8ULL1
- Every structure of UniProt A0A6A5Q3S9
- Elsewhere: RCSB PDB 8AGC · PDBe 8AGC · UniProt A0A6A5Q0M3 · UniProt A0A8H8UM72 · UniProt Q92316 · UniProt A0A8H4BUV6 · UniProt A0A6A5PXA1 · UniProt A0A6V8S2Y6 · UniProt A0A8H8ULL1 · UniProt A0A6A5Q3S9
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