MolNFT v2 · #198892 · protein
Fungal immunomodulatory protein FIP-nha
7WDL: “Fungal immunomodulatory protein FIP-nha”. X-ray diffraction at 1.903, 8 pockets (best druggability 0.44). MolNFT v2 #198892 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7WDL
- Type
- protein
- Length
- 448 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.903
- Source
- Fusarium solani
- Molecule
- Fungal immunomodulatory protein
- UniProt
- C7ZE17
- Pockets
- 8 · best druggability 0.44
Structure
x-ray diffraction · resolution 1.903 · 3 distinct chains · 13% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Fungal immunomodulatory protein | protein | 111 | 13% helix, 43% strand | C7ZE17 |
| A, D | Fungal immunomodulatory protein | protein | 112 | 13% helix, 43% strand | C7ZE17 |
| C | Fungal immunomodulatory protein | protein | 113 | 12% helix, 42% strand | C7ZE17 |
Pockets
8 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 96 | 0.44 | 0.79 | 20 | empty |
| 2 | 104 | 0.42 | 0.77 | 23 | empty |
| 3 | 79 | 0.40 | 0.79 | 22 | empty |
| 4 | 54 | 0.38 | 0.80 | 19 | empty |
| 5 | 82 | 0.35 | 0.75 | 19 | empty |
Interfaces
6 interfaces between chains.
- A–C · 1497 Ų buried · 25 hydrogen bonds · protein-protein
- B–D · 1480 Ų buried · 24 hydrogen bonds · protein-protein
- A–D · 627 Ų buried · 9 hydrogen bonds · protein-protein
- B–C · 625 Ų buried · 8 hydrogen bonds · protein-protein
- C–D · 120 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7WDL · Fungal immunomodulatory protein fip-nha · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C7ZE17
- Elsewhere: RCSB PDB 7WDL · PDBe 7WDL · UniProt C7ZE17
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