MolNFT v2 · #195361 · protein
Crystal structure of JAK2 JH1 with type II inhibitor YLIU-04-105-1
7TEU: “Crystal structure of JAK2 JH1 with type II inhibitor YLIU-04-105-1”. X-ray diffraction at 1.45, 1 ligand (I6C). MolNFT v2 #195361 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7TEU
- Type
- protein
- Length
- 276 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.45
- Source
- Homo sapiens
- UniProt
- O60674
- Ligands
- I6C
Structure
x-ray diffraction · resolution 1.45 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 276 | — | O60674 |
Ligands and binding sites
- I6C · 3-{(4S)-2-[(cyclopropanecarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}-N-{3-[(4-ethylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}-4-methylbenzamide · ligand · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60674
- Elsewhere: RCSB PDB 7TEU · PDBe 7TEU · UniProt O60674
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