MolNFT v2 · #194851 · protein
NIK bound to inhibitor G02792917
7SZR: “NIK bound to inhibitor G02792917”. X-ray diffraction at 2.8, 2 ligands (DYQ, SO4). MolNFT v2 #194851 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7SZR
- Type
- protein
- Length
- 649 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.8
- Source
- Mus musculus
- UniProt
- Q9WUL6
- Ligands
- DYQ, SO4
Structure
x-ray diffraction · resolution 2.8 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 321 | — | Q9WUL6 |
| B | — | protein | 328 | — | Q9WUL6 |
Ligands and binding sites
- DYQ · 1-(3-{[(1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2-azabicyclo[3.1.0]hexan-4-yl]ethynyl}phenyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- Q9WUL6 · AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase kinase kinase 14… · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WUL6
- Elsewhere: RCSB PDB 7SZR · PDBe 7SZR · UniProt Q9WUL6
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