MolNFT v2 · #185384 · protein
Crystal structure of the first bromodomain (BD1) of human BRDT bound to ERK5-IN-1
7L73: “Crystal structure of the first bromodomain (BD1) of human BRDT bound to ERK5-IN-1”. X-ray diffraction at 1.46, 1 ligand (VYJ). MolNFT v2 #185384 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7L73
- Type
- protein
- Length
- 112 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.46
- Source
- Homo sapiens
- UniProt
- Q58F21
- Ligands
- VYJ
Structure
x-ray diffraction · resolution 1.46 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 112 | — | Q58F21 |
Ligands and binding sites
- VYJ · 11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7L73 · Crystal structure of the first bromodomain (BD1) of human brdt bound to ERK5-in-1 · the same entry in another collection · chain A against A, TM-score 1.00
- Q58F21 · AlphaFold monomer V2.0 prediction for bromodomain testis-specific protein (Q58F21) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q58F21
- Elsewhere: RCSB PDB 7L73 · PDBe 7L73 · UniProt Q58F21
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