MolNFT v2 · #183486 · protein
Crystal structure of schistosome BCL-2 bound to ABT-737
7JMT: “Crystal structure of schistosome BCL-2 bound to ABT-737”. X-ray diffraction at 2.75, 1 ligand (N3C). MolNFT v2 #183486 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7JMT
- Type
- protein
- Length
- 955 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.75
- Source
- Schistosoma japonicum
- UniProt
- Q5BWX6
- Ligands
- N3C
Structure
x-ray diffraction · resolution 2.75 · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, F | — | protein | 161 | — | Q5BWX6 |
| B | — | protein | 156 | — | Q5BWX6 |
| C | — | protein | 165 | — | Q5BWX6 |
| D | — | protein | 156 | — | Q5BWX6 |
| E | — | protein | 156 | — | Q5BWX6 |
Ligands and binding sites
- N3C · 4-{4-[(4'-chlorobiphenyl-2-yl)methyl]piperazin-1-yl}-N-{[4-({(1R)-3-(dimethylamino)-1-[(phenylthio) methyl]propyl}amino)-3-nitrophenyl]sulfonyl}benzamide · ligand · 6 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7JMT · Crystal structure of schistosome BCL-2 bound to abt-737 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5BWX6
- Elsewhere: RCSB PDB 7JMT · PDBe 7JMT · UniProt Q5BWX6
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