MolNFT v2 · #175588 · protein
Crystal structure of BRD4(1) in complex with the inhibitor MPM6
7B1T: “Crystal structure of BRD4(1) in complex with the inhibitor MPM6”. X-ray diffraction at 1.92, 1 ligand (SOK). MolNFT v2 #175588 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7B1T
- Type
- protein
- Length
- 127 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.92
- Source
- Homo sapiens
- UniProt
- O60885
- Ligands
- SOK
Structure
x-ray diffraction · resolution 1.92 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 127 | — | O60885 |
Ligands and binding sites
- SOK · 3-(5-azanyl-2-chloranyl-phenyl)-1-methyl-4,7-dihydro-2~{H}-cyclohepta[c]pyrrol-8-one · ligand · chains A
- DMS · Dimethyl sulfoxide · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7B1T · Crystal structure of BRD4(1) in complex with the inhibitor MPM6 · the same entry in another collection · chain A against A, TM-score 1.00
- O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60885
- Elsewhere: RCSB PDB 7B1T · PDBe 7B1T · UniProt O60885
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.