MolNFT v2 · #169020 · protein
JAK2 JH1 in complex with PN4-073
6VNK: “JAK2 JH1 in complex with PN4-073”. X-ray diffraction at 2, 1 ligand (RXT). MolNFT v2 #169020 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6VNK
- Type
- protein
- Length
- 1,172 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2
- Source
- Homo sapiens
- UniProt
- O60674
- Ligands
- RXT
Structure
x-ray diffraction · resolution 2 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D, C | — | protein | 289 | — | O60674 |
| B, A | — | protein | 297 | — | O60674 |
Ligands and binding sites
- RXT · (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile · ligand · 4 copies · chains D, B, C, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6VNK · JAK2 JH1 in complex with PN4-073 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60674
- Elsewhere: RCSB PDB 6VNK · PDBe 6VNK · UniProt O60674
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