MolNFT v2 · #169019 · protein
JAK2 JH1 in complex with PN4-014
6VNJ: “JAK2 JH1 in complex with PN4-014”. X-ray diffraction at 1.9, 1 ligand (R5S). MolNFT v2 #169019 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6VNJ
- Type
- protein
- Length
- 589 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.9
- Source
- Homo sapiens
- UniProt
- O60674
- Ligands
- R5S
Structure
x-ray diffraction · resolution 1.9 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 290 | — | O60674 |
| A | — | protein | 299 | — | O60674 |
Ligands and binding sites
- R5S · 3-[4-(2-{[4-(piperidin-4-yl)phenyl]amino}-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile · ligand · 2 copies · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6VNJ · JAK2 JH1 in complex with PN4-014 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60674
- Elsewhere: RCSB PDB 6VNJ · PDBe 6VNJ · UniProt O60674
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