MolNFT v2 · #165311 · protein
Crystal structure of human ROR gamma LBD in complex with a (quinolinoxymethyl)benzamide inverse agonist
6SLZ: “Crystal structure of human ROR gamma LBD in complex with a (quinolinoxymethyl)benzamide inverse agonist”. X-ray diffraction at 2.2, 1 ligand (LK8). MolNFT v2 #165311 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6SLZ
- Type
- protein
- Length
- 436 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.2
- Source
- Homo sapiens
- UniProt
- P51449
- Ligands
- LK8
Structure
x-ray diffraction · resolution 2.2 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 218 | — | P51449 |
| B | — | protein | 218 | — | P51449 |
Ligands and binding sites
- LK8 · (2~{S})-1-[2,4-bis(chloranyl)-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]carbonyl-~{N}-methyl-pyrrolidine-2-carboxamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6SLZ · Crystal structure of human ror gamma lbd in complex with a (QUINOLINOXYMETHYL)BENZAMIDE… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51449
- Elsewhere: RCSB PDB 6SLZ · PDBe 6SLZ · UniProt P51449
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