MolNFT v2 · #164105 · protein
Structure of IMP bound Plasmodium falciparum IMP-nucleotidase mutant D172N
6RME: “Structure of IMP bound Plasmodium falciparum IMP-nucleotidase mutant D172N”. X-ray diffraction at 3.4, 2 ligands (IMP, MG). MolNFT v2 #164105 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6RME
- Type
- protein
- Length
- 3,010 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.4
- Source
- Plasmodium falciparum (isolate 3D7)
- UniProt
- A0A144A134
- Ligands
- IMP, MG
Structure
x-ray diffraction · resolution 3.4 · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 373 | — | A0A144A134 |
| B, D | — | protein | 375 | — | A0A144A134 |
| C | — | protein | 385 | — | A0A144A134 |
| E, H | — | protein | 376 | — | A0A144A134 |
| F | — | protein | 378 | — | A0A144A134 |
| G | — | protein | 372 | — | A0A144A134 |
Ligands and binding sites
- IMP · Inosinic acid · ligand · 8 copies · chains A, B, C, D, E, F, G, H
- MG · Magnesium ion · metal · 8 copies · chains A, B, C, D, E, F, G, H
- GOL · Glycerol · additive · 2 copies · chains D, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6RME · Structure of imp bound plasmodium falciparum imp-nucleotidase mutant D172N · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A144A134
- Elsewhere: RCSB PDB 6RME · PDBe 6RME · UniProt A0A144A134
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.