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MolNFT v2 · #159959 · protein

Structure of the TRPM8 cold receptor by single particle electron cryo-microscopy, AMTB-bound state

6O6R: “Structure of the TRPM8 cold receptor by single particle electron cryo-microscopy, AMTB-bound state”. Electron microscopy at 3.2, 4 ligands (Y01, 9PE, LQ7). MolNFT v2 #159959 on GenesisL1: 3D structure, binding sites and pockets in…

PDB
6O6R
Type
protein
Length
3,332 residues
Chains
4
Method
electron microscopy
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
3.2
Source
Parus major
Ligands
Y01, 9PE, LQ7, NA

Structure

electron microscopy · resolution 3.2 · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D—protein833——

Ligands and binding sites

  • Y01 · Cholesterol hemisuccinate · ligand · 4 copies · chains A, B, C, D
  • 9PE · (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate · ligand · 4 copies · chains A, D, B, C
  • LQ7 · N-(3-aminopropyl)-2-[(3-methylphenyl)methoxy]-N-[(thiophen-2-yl)methyl]benzamide · ligand · 4 copies · chains A, B, C, D
  • NA · Sodium ion · metal · 8 copies · chains A, B, C, D
  • UND · Undecane · additive · 8 copies · chains A, D, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6O6R · Structure of the TRPM8 cold receptor by single particle electron cryo- microscopy… · the same entry in another collection · chain A against A, TM-score 1.00

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