MolNFT v2 · #159831 · protein

Structure of cruzain bound to MMTS inhibitor

6O2X: “Structure of cruzain bound to MMTS inhibitor”. X-ray diffraction at 1.193, 1 ligand (PO4). MolNFT v2 #159831 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6O2X
Type: protein
Length: 430 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.193
Source: Trypanosoma cruzi
UniProt: P25779
Ligands: PO4

Structure

x-ray diffraction · resolution 1.193 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	215	—	P25779

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A
EDO · 1,2-ethanediol · additive · 6 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6O2X · Structure of cruzain bound to mmts inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
P25779 · AlphaFold monomer V2.0 prediction for cruzipain (P25779) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P25779
Elsewhere: RCSB PDB 6O2X · PDBe 6O2X · UniProt P25779

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