MolNFT v2 · #159519 · protein
Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by (S) Stereoisomer of A-232
6NTH: “Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by (S) Stereoisomer of A-232”. X-ray diffraction at 2.421, 3 ligands (L0S, NAG, FUC). MolNFT v2 #159519 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6NTH
- Type
- protein
- Length
- 1,064 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.421
- Source
- Homo sapiens
- UniProt
- P22303
- Ligands
- L0S, NAG, FUC
Structure
x-ray diffraction · resolution 2.421 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 534 | — | P22303 |
| B | — | protein | 530 | — | P22303 |
Ligands and binding sites
- L0S · methyl (R)-N-[(1E)-1-(diethylamino)ethylidene]-P-methylphosphonamidate · ligand · 2 copies · chains A, B
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 8 copies · chains A, B
- FUC · alpha-L-fucopyranose · sugar · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6NTH · Crystal structure of recombinant human acetylcholinesterase inhibited by (S) stereoisomer… · the same entry in another collection · chain A against A, TM-score 1.00
- P22303 · AlphaFold monomer V2.0 prediction for acetylcholinesterase (P22303) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22303
- Elsewhere: RCSB PDB 6NTH · PDBe 6NTH · UniProt P22303
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