MolNFT v2 · #158538 · protein

Crystal structure of SESTRIN2 in complex with nv-0005138

6N0M: “Crystal structure of SESTRIN2 in complex with nv-0005138”. X-ray diffraction at 3.3, 1 ligand (K94). MolNFT v2 #158538 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6N0M
Type: protein
Length: 1,824 residues
Chains: 5
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.3
Source: Homo sapiens
UniProt: P58004
Ligands: K94

Structure

x-ray diffraction · resolution 3.3 · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	366	—	P58004
B	—	protein	365	—	P58004
C	—	protein	364	—	P58004
D	—	protein	364	—	P58004
E	—	protein	365	—	P58004

Ligands and binding sites

K94 · 4-(difluoromethyl)-L-leucine · ligand · 5 copies · chains A, B, C, D, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6N0M · Crystal structure of SESTRIN2 in complex with nv-0005138 · the same entry in another collection · chain E against E, TM-score 1.00
P58004 · AlphaFold monomer V2.0 prediction for sestrin-2 (P58004) · a predicted model of the same protein · chain B against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P58004
Elsewhere: RCSB PDB 6N0M · PDBe 6N0M · UniProt P58004

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