MolNFT v2 · #157411 · protein

KCC3 bound with DIOA

6M22: “KCC3 bound with DIOA”. Electron microscopy at 2.7, 4 ligands (EZC, NAG, K). MolNFT v2 #157411 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6M22
Type: protein
Length: 1,770 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.7
Source: Homo sapiens
UniProt: Q9UHW9
Ligands: EZC, NAG, K, CL

Structure

electron microscopy · resolution 2.7 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	885	—	Q9UHW9

Ligands and binding sites

EZC · 2-[[(2~{R})-2-butyl-6,7-bis(chloranyl)-2-cyclopentyl-1-oxidanylidene-3~{H}-inden-5-yl]oxy]ethanoic acid · ligand · 2 copies · chains A, B
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 16 copies · chains A, B
K · Potassium ion · metal · 2 copies · chains A, B
CL · Chloride ion · ion · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6M22 · KCC3 bound with dioa · the same entry in another collection · chain A against A, TM-score 1.00
Q9UHW9 · AlphaFold monomer V2.0 prediction for solute carrier family 12 member 6 (Q9UHW9) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UHW9
Elsewhere: RCSB PDB 6M22 · PDBe 6M22 · UniProt Q9UHW9

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