MolNFT v2 · #1556 · protein

Rat ferrocytochrome B5 a conformation, NMR, 1 structure

1B5A: “Rat ferrocytochrome B5 a conformation, NMR, 1 structure”. Solution nmr at NOT, 1 ligand (HEM), 2 pockets (best druggability 0.65). MolNFT v2 #1556 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1B5A
Type: protein
Length: 94 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: NOT
Source: Rattus norvegicus
Molecule: Ferrocytochrome B5
UniProt: P00173
Ligands: HEM
Pockets: 2 · best druggability 0.65

Structure

solution nmr · resolution NOT · 1 distinct chain · 29% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ferrocytochrome B5	protein	94	29% helix, 19% strand	P00173

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	171	0.65	0.85	24	HEM
2	52	0.30	0.76	16	empty

Compared structures

1B5A · Rat ferrocytochrome B5 a conformation, NMR, 1 structure · the same entry in another collection · chain A against A, TM-score 1.00
P00173 · AlphaFold monomer V2.0 prediction for cytochrome B5 (P00173) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00173
Elsewhere: RCSB PDB 1B5A · PDBe 1B5A · UniProt P00173

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