MolNFT v2 · #154959 · protein
Crystal structure of human MTH1 in complex with compound MI1012
6JVK: “Crystal structure of human MTH1 in complex with compound MI1012”. X-ray diffraction at 2.1, 1 ligand (CEU). MolNFT v2 #154959 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6JVK
- Type
- protein
- Length
- 305 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.1
- Source
- Homo sapiens
- UniProt
- P36639
- Ligands
- CEU
Structure
x-ray diffraction · resolution 2.1 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 154 | — | P36639 |
| B | — | protein | 151 | — | P36639 |
Ligands and binding sites
- CEU · N4-methyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6JVK · Crystal structure of human MTH1 in complex with compound MI1012 · the same entry in another collection · chain A against A, TM-score 1.00
- P36639 · AlphaFold monomer V2.0 prediction for 7,8-dihydro-8-oxoguanine triphosphatase (P36639) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P36639
- Elsewhere: RCSB PDB 6JVK · PDBe 6JVK · UniProt P36639
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