MolNFT v2 · #153927 · protein
Crystal structure of aminoglycoside 7"-phoshotransferase-Ia (APH(7")-Ia/HYG) from Streptomyces hygroscopicus complexed with hygromycin B
6IY9: “Crystal structure of aminoglycoside 7"-phoshotransferase-Ia (APH(7")-Ia/HYG) from Streptomyces hygroscopicus…”. X-ray diffraction at 2.4, 1 ligand (HY0). MolNFT v2 #153927 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6IY9
- Type
- protein
- Length
- 649 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.4
- Source
- Streptomyces hygroscopicus
- UniProt
- P09979
- Ligands
- HY0
Structure
x-ray diffraction · resolution 2.4 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 325 | — | P09979 |
| B | — | protein | 324 | — | P09979 |
Ligands and binding sites
- HY0 · Hygromycin B variant · ligand · 2 copies · chains A, B
- NHE · 2-[N-cyclohexylamino]ethane sulfonic acid · additive · 2 copies · chains A, B
- FLC · Citrate anion · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6IY9 · Crystal structure of aminoglycoside 7"-phoshotransferase-ia (APH(7")- IA/HYG) from… · the same entry in another collection · chain A against A, TM-score 1.00
- P09979 · AlphaFold monomer V2.0 prediction for hygromycin-B 7''-O-kinase (P09979) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09979
- Elsewhere: RCSB PDB 6IY9 · PDBe 6IY9 · UniProt P09979
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