MolNFT v2 · #153488 · protein
Crystal structure of PDE10 in complex with inhibitor 2b
6IJI: “Crystal structure of PDE10 in complex with inhibitor 2b”. X-ray diffraction at 2.7, 3 ligands (AEL, ZN, MG). MolNFT v2 #153488 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6IJI
- Type
- protein
- Length
- 636 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.7
- Source
- Homo sapiens
- UniProt
- Q9Y233
- Ligands
- AEL, ZN, MG
Structure
x-ray diffraction · resolution 2.7 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 324 | — | Q9Y233 |
| B | — | protein | 312 | — | Q9Y233 |
Ligands and binding sites
- AEL · 2-{2-[5-methyl-1-(pyridin-4-yl)-1H-benzimidazol-2-yl]ethyl}-1H-benzo[de]isoquinoline-1,3(2H)-dione · ligand · chains B
- ZN · Zinc ion · metal · 2 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6IJI · Crystal structure of PDE10 in complex with inhibitor 2B · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y233
- Elsewhere: RCSB PDB 6IJI · PDBe 6IJI · UniProt Q9Y233
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.