MolNFT v2 · #152853 · protein
Crystal structure of human carbonic anhydrase I in complex with the 4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl sulfamate inhibitor
6I0J: “Crystal structure of human carbonic anhydrase I in complex with the…”. X-ray diffraction at 1.35, 2 ligands (GZE, ZN). MolNFT v2 #152853 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6I0J
- Type
- protein
- Length
- 514 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.35
- Source
- Homo sapiens
- UniProt
- P00915
- Ligands
- GZE, ZN
Structure
x-ray diffraction · resolution 1.35 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 257 | — | P00915 |
Ligands and binding sites
- GZE · [4-[[4-chloranyl-3-(trifluoromethyl) phenyl]carbamoylamino]phenyl] sulfamate · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · 2 copies · chains A, B
- GOL · Glycerol · additive · 3 copies · chains A, B
- ACT · Acetate ion · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6I0J · Crystal structure of human carbonic anhydrase I in complex with the 4… · the same entry in another collection · chain A against A, TM-score 1.00
- P00915 · AlphaFold monomer V2.0 prediction for carbonic anhydrase 1 (P00915) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00915
- Elsewhere: RCSB PDB 6I0J · PDBe 6I0J · UniProt P00915
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