MolNFT v2 · #151675 · protein
Crystal structure of Mdm2 bound to a stapled peptide
6H22: “Crystal structure of Mdm2 bound to a stapled peptide”. X-ray diffraction at 2.006, 1 ligand (FL5). MolNFT v2 #151675 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6H22
- Type
- protein
- Length
- 207 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.006
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- Q00987
- Ligands
- FL5
Structure
x-ray diffraction · resolution 2.006 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 91 | — | Q00987 |
| B | — | protein | 92 | — | Q00987 |
| C, D | — | protein | 12 | — | — |
Ligands and binding sites
- FL5 · 12-(dimethylamino)-3,10-diethyl-N,N,N-trimethyl-3,10-dihydrodibenzo[3,4:7,8]cycloocta[1,2-D:5,6-d']bis([1, 2,3]triazole)-5-aminium · ligand · 2 copies · chains A, C, B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6H22 · Crystal structure of MDM2 bound to a stapled peptide · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q00987
- Elsewhere: RCSB PDB 6H22 · PDBe 6H22 · UniProt Q00987
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