MolNFT v2 · #147474 · protein
Human mitochondrial ClpP in complex with ONC201 (TIC10)
6DL7: “Human mitochondrial ClpP in complex with ONC201 (TIC10)”. X-ray diffraction at 2, 1 ligand (ONC). MolNFT v2 #147474 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6DL7
- Type
- protein
- Length
- 1,244 residues
- Chains
- 7
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2
- Source
- Homo sapiens
- UniProt
- Q16740
- Ligands
- ONC
Structure
x-ray diffraction · resolution 2 · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 175 | — | Q16740 |
| B | — | protein | 174 | — | Q16740 |
| C | — | protein | 178 | — | Q16740 |
| D | — | protein | 177 | — | Q16740 |
| E | — | protein | 180 | — | Q16740 |
| F | — | protein | 179 | — | Q16740 |
| G | — | protein | 181 | — | Q16740 |
Ligands and binding sites
- ONC · 7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one · ligand · 7 copies · chains A, G, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6DL7 · Human mitochondrial clpp in complex with ONC201 (TIC10) · the same entry in another collection · chain G against G, TM-score 1.00
- Q16740 · AlphaFold monomer V2.0 prediction for ATP-dependent clp protease proteolytic subunit… · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16740
- Elsewhere: RCSB PDB 6DL7 · PDBe 6DL7 · UniProt Q16740
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