MolNFT v2 · #137912 · protein
Crystal structure of human MYT1 kinase domain in complex with MK1775
5VD0: “Crystal structure of human MYT1 kinase domain in complex with MK1775”. X-ray diffraction at 2.13, 1 ligand (8X7). MolNFT v2 #137912 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5VD0
- Type
- protein
- Length
- 293 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.13
- Source
- Homo sapiens
- UniProt
- Q99640
- Ligands
- 8X7
Structure
x-ray diffraction · resolution 2.13 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 293 | — | Q99640 |
Ligands and binding sites
- 8X7 · 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one · ligand · chains A
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5VD0 · Crystal structure of human MYT1 kinase domain in complex with MK1775 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99640
- Elsewhere: RCSB PDB 5VD0 · PDBe 5VD0 · UniProt Q99640
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