MolNFT v2 · #136921 · protein
Crystal structure of IRAK4 in complex with compound 9
5UIQ: “Crystal structure of IRAK4 in complex with compound 9”. X-ray diffraction at 2.64, 1 ligand (8BV). MolNFT v2 #136921 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5UIQ
- Type
- protein
- Length
- 1,103 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.64
- Source
- Homo sapiens
- UniProt
- Q9NWZ3
- Ligands
- 8BV
Structure
x-ray diffraction · resolution 2.64 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 271 | — | Q9NWZ3 |
| B | — | protein | 275 | — | Q9NWZ3 |
| C | — | protein | 283 | — | Q9NWZ3 |
| D | — | protein | 274 | — | Q9NWZ3 |
Ligands and binding sites
- 8BV · 2-[(propan-2-yl)oxy]benzamide · ligand · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5UIQ · Crystal structure of IRAK4 in complex with compound 9 · the same entry in another collection · chain D against D, TM-score 1.00
- Q9NWZ3 · AlphaFold monomer V2.0 prediction for interleukin-1 receptor- associated kinase 4 (Q9NWZ3) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NWZ3
- Elsewhere: RCSB PDB 5UIQ · PDBe 5UIQ · UniProt Q9NWZ3
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