P.vivax NMT with aminomethylindazole and quinoline inhibitors bound

Structure

x-ray diffraction · resolution 1.7 · 2 distinct chains.

Ligands and binding sites

• NHW · 2-oxopentadecyl-CoA · ligand · 3 copies · chains A, B, C
• 9K2 · 1-[5-(4-fluoranyl-2-methyl-phenyl)-1~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine · ligand · 3 copies · chains A, B, C
• 9KZ · ethyl 2,4-dimethylquinoline-3-carboxylate · ligand · 3 copies · chains A, B, C
• MG · Magnesium ion · metal · 3 copies · chains A, B, C
• SO4 · Sulfate ion · ion · 4 copies · chains A, B, C
• CL · Chloride ion · ion · 3 copies · chains A, B, C
• DMS · Dimethyl sulfoxide · additive · 3 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 5O4V · P.VIVAX nmt with aminomethylindazole and quinoline inhibitors bound · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A5K1A2
• Elsewhere: RCSB PDB 5O4V · PDBe 5O4V · UniProt A5K1A2